Model for actin-based motility
1. Signal-mediated activation of N-WASp, the branching enzyme
2. G-actin, Arp2/3 and filaments as substrates of N-WASp
3. Dissociation of the branch (product) and recycling
Question: Role of ATP exchange and hydrolysis on Arp2/3 in the branching and recycling of Arp2/3 complex ?