Actin-based Motility

ATP hydrolysis on Arp2/3 drives filament debranching

ATP

G

ATP

2

ATP

3

ATP

2

ATP

3

ADP

G

ATP

2

ATP

3

ADP

G

Pi

ATP

3

ADP

2

ATP

G

ATP

2

ATP

3

Arp2/3

Inactif

ATP

2

ATP

3

Arp2/3

Activé

WA

Pi