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Multiscale Modeling in Cell Biology (2006)

Organizers: Yasmin Dolak-Struß (U. of Vienna), V. Small (IMBA, Vienna)

In the last decades, the development of new experimental methods and tools has allowed to gain new insights into the biological, chemical and mechanical nature of cell biology. However, biologists are still far away from having a complete picture. Mathematical modelling is an important tool to get a deeper understanding of the observed biological phenomena as well as to provide means to test different hypotheses and theories formulated by the experimentalists. Due to the complexity of the processes involved, a close interaction between experimentalists and mathematicians is needed in order to develop efficient mathematical models.

This thematic program aims to provide the framework for a successful cooperation between theory and experiment, with an emphasis on both the mathematical methods and the experimental facts.

A major part of the thematic program will be dedicated to the mathematical modeling of cell crawling. This process is essential for many biological processes such as wound healing or the immune response of our body. In most crawling cells, movement is driven by the actin cytoskeleton, a protein network inside the cell. This network is constantly being reorganized, growing at the front of the cell and contracting at the rear while exerting force to the substrate via particular adhesion proteins. The mathematical description of this process is indeed challenging, as chemical signals inside the cell contribute to changes in the structure of the network as well as external chemical or mechanical stimuli. Understanding these cytoskeletal dynamics has become a focus of research in Vienna – both experimentally (Small group, IMBA) and, quite recently, also from a mathematical point of view (Schmeiser group, WPI/U. of Vienna).
Other topics of the thematic program will include the mathematical modeling of actin-based motility as observed in the bacterial pathogen Listeria or biomimetic in vitro systems, and cell movement on the level of cell populations, with a particular focus on chemotaxis.

Events

Mathematical Modelling of Actin-Based Motility

Location: IMBA, Dr. Bohrg. 3, 1030 Vienna
Time: 6. Nov 2006 (Mon) - 8. Nov 2006 (Wed); Opening: 9:00
Organisation(s)
WPI
IMBA/IMP
WWTF
WK Differential Equations
Organiser(s)
Yasmin Dolak-Struß (U.Wien)
Vic Small (IMBA)
Christian Schmeiser (WPI c/o U.Wien)
Remark: Contact:
Yasmin Dolak-Struß (yasmin.dolak-struss@univie.ac.at)

Talks in the framework of this thematic program... (by date) , (by name)

Visitors

Anderson, Kurt 7. Nov 2006-8. Nov 2006 local address 
Burroughs, Nigel 2. Nov 2006-8. Nov 2006 local address 
Carlier, Marie-France 4. Nov 2006-8. Nov 2006 local address 
Carlsson, Anders 5. Nov 2006-9. Nov 2006 local address 
Chaker, Hedia 26. Mar 2006-2. Apr 2006 local address 
Danuser, Gaudenz 6. Nov 2006-9. Nov 2006 local address 
Dickinson, Richard 5. Nov 2006-9. Nov 2006 local address 
Dunn, Graham 4. Nov 2006-9. Nov 2006 local address 
Erban, Radek 6. Jun 2006-10. Jun 2006 local address 
Gov, Nir 5. Nov 2006-9. Nov 2006 local address 
Hilhorst, Danielle 20. Mar 2006-23. Mar 2006 local address 
Landa-Levy, Marianna 7. Sep 2006-17. Sep 2006 local address 
Levy, Doron 7. Sep 2006-17. Sep 2006 local address 
25. Nov 2006-28. Nov 2006 local address 
Malchiodi, Andrea 20. Mar 2006-22. Mar 2006 local address 
Mannherz, Hans Georg 5. Nov 2006-8. Nov 2006 local address 
Maree, Stan 5. Nov 2006-9. Nov 2005 local address 
Mimura, Masayasu 20. Mar 2006-23. Mar 2006 local address 
Münch, Andreas 4. Apr 2006-5. Apr 2006 local address 
Nazarov, Petr 5. Nov 2006-8. Nov 2006 local address 
Othmer, Hans 5. Nov 2006-9. Nov 2006 local address 
Ovryn, Ben 5. Nov 2006-8. Nov 2006 local address 
Paluch, Ewa 27. Sep 2006-29. Sep 2006 local address 
4. Nov 2006-9. Nov 2006 local address 
Perthame, Benoit 20. Mar 2006-22. Mar 2006 local address 
Plastino, Julie 5. Nov 2001-9. Nov 2006 local address 
Poujade, Matthieu 4. Nov 2006-8. Nov 2006 local address 
Rottner, Klemens 5. Nov 2006-8. Nov 2006 local address 
Rybka, Piotr 20. Mar 2006-23. Mar 2006 local address 
Shlomovitz, Roie 5. Nov 2006-12. Nov 2006 local address 
Soong, Daniel 5. Nov 2006-9. Nov 2006 local address 
Svitkina, Tatyana 5. Nov 2006-8. Nov 2006 local address 
Tayeb, Mohamed Lazhar 23. Apr 2006-12. May 2006 local address 
Terracini, Susanna 20. Mar 2006-24. Mar 2006 local address 
Tinevez, Jean-Yves 4. Nov 2006-9. Nov 2006 local address 
van der Gucht, Jasper 5. Nov 2006-8. Nov 2006 local address 
Verkhovsky, Alexander 5. Nov 2006-8. Nov 2006 local address 
Verzini, Gianmaria 20. Mar 2006-24. Mar 2006 local address 
Voituriez, Raphael 5. Nov 2006-7. Nov 2006 local address 
Yatskou, Mikalai 5. Nov 2006-8. Nov 2006 local address 
Zumdieck, Alexander 27. Sep 2006-29. Sep 2006 local address 

PostDocs

Dolak-Struß, Yasmin 1. Jan 2006-31. Dec 2006 local address 
Fellner, Klemens 1. Jan 2006-31. Dec 2006 local address 

PreDocs

Wang, Zhian 23. Sep 2006-3. Oct 2006 local address 
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